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GPR77 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GPR77 Antibody (C-term) AP20046b
    GPR77 Antibody (C-term) (Cat. #AP20046b) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the GPR77 antibody detected the GPR77 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9P296
Other Accession NP_060955.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 36080 Da
Antigen Region 297-325 aa
Additional Information
Gene ID 27202
Other Names C5a anaphylatoxin chemotactic receptor 2, Complement component 5a receptor 2, G-protein coupled receptor 77, C5AR2, C5L2, GPR77
Target/Specificity This GPR77 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 297-325 amino acids from the C-terminal region of human GPR77.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGPR77 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name C5AR2
Synonyms C5L2, GPR77
Function Receptor for the chemotactic and inflammatory C3a, C4a and C5a anaphylatoxin peptides and also for their dearginated forms ASP/C3adesArg, C4adesArg and C5adesArg respectively. Couples weakly to G(i)-mediated signaling pathways.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Frontal cortex, hippocampus, hypothalamus, pons and liver.
Research Areas
Citations (0)

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The anaphylatoxins C3a (see MIM 120700), C4a (see MIM 120810), and C5a are cationic fragments generated during the complement cascade that participate in host defense. In the case of inappropriate complement activation, anaphylatoxins may be involved in autoimmunity and sepsis. C5L2 is coexpressed with the C5a receptor, C5AR (C5R1; MIM 113995), on polymorphonuclear neutrophils and may modulate C5AR activity (Gerard et al., 2005 [PubMed 16204243]).


Bamberg, C.E., et al. J. Biol. Chem. 285(10):7633-7644(2010)
Cui, W., et al. Mol. Immunol. 46(16):3207-3217(2009)
Cui, W., et al. Mol. Immunol. 46(15):3086-3098(2009)
Scola, A.M., et al. Mol. Immunol. 46(6):1149-1162(2009)
Scola, A.M., et al. J. Biol. Chem. 282(6):3664-3671(2007)

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$ 295.00
$ 99.00
Cat# AP20046b
(40 western blots)
Availability: In Stock
Bulk Size
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