|Application ||WB, E|
|Calculated MW||45717 Da|
|Antigen Region||201-230 aa|
|Other Names||Procollagen C-endopeptidase enhancer 2, Procollagen COOH-terminal proteinase enhancer 2, PCPE-2, Procollagen C-proteinase enhancer 2, PCOLCE2, PCPE2|
|Target/Specificity||This PCOLCE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-230 amino acids from the Central region of human PCOLCE2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PCOLCE2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1.|
|Tissue Location||Highly expressed in the heart, trabecular meshwork, pituitary gland, bladder, mammary gland, trachea and placenta and weakly expressed in the brain. Expressed in cartilage.|
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Provided below are standard protocols that you may find useful for product applications.
PCOLCE2 binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1.
Zhu, J., et al. J. Lipid Res. 50(7):1330-1339(2009)
Steiglitz, B.M., et al. J. Biol. Chem. 277(51):49820-49830(2002)
Steiglitz, B.M., et al. Cytogenet. Cell Genet. 95 (3-4), 244-245 (2001) :
Xu, H., et al. Genomics 66(3):264-273(2000)
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