|Application ||WB, E|
|Calculated MW||67595 Da|
|Antigen Region||21-49 aa|
|Other Names||PiggyBac transposable element-derived protein 3, PGBD3|
|Target/Specificity||This PGBD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-49 amino acids from the N-terminal region of human PGBD3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PGBD3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
The piggyBac family of proteins, found in diverse animals, are transposases related to the transposase of the canonical piggyBac transposon from the moth, Trichoplusia ni. This family also includes genes in several genomes, including human, that appear to have been derived from the piggyBac transposons. This gene belongs to the subfamily of piggyBac transposable element derived (PGBD) genes. The PGBD proteins appear to be novel, with no obvious relationship to other transposases, or other known protein families. This gene overlaps with the ERCC6 gene on chromosome 10, and pseudogenes of this locus have been found on chromosomes 4, 5 and 12.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Newman, J.C., et al. PLoS Genet. 4 (3), E1000031 (2008) :
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Sarkar, A., et al. Mol. Genet. Genomics 270(2):173-180(2003)
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