|Application ||WB, E|
|Calculated MW||67595 Da|
|Antigen Region||21-49 aa|
|Other Names||PiggyBac transposable element-derived protein 3, PGBD3|
|Target/Specificity||This PGBD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-49 amino acids from the N-terminal region of human PGBD3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PGBD3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds in vitro to PGBD3-related transposable elements, called MER85s; these non-autonomous 140 bp elements are characterized by the presence of PGBD3 terminal inverted repeats and the absence of internal transposase ORF.|
|Tissue Location||Expressed in heart and oocytes, but not in granulosa cells (at protein level).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The piggyBac family of proteins, found in diverse animals, are transposases related to the transposase of the canonical piggyBac transposon from the moth, Trichoplusia ni. This family also includes genes in several genomes, including human, that appear to have been derived from the piggyBac transposons. This gene belongs to the subfamily of piggyBac transposable element derived (PGBD) genes. The PGBD proteins appear to be novel, with no obvious relationship to other transposases, or other known protein families. This gene overlaps with the ERCC6 gene on chromosome 10, and pseudogenes of this locus have been found on chromosomes 4, 5 and 12.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Newman, J.C., et al. PLoS Genet. 4 (3), E1000031 (2008) :
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Sarkar, A., et al. Mol. Genet. Genomics 270(2):173-180(2003)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.