|Application ||WB, E|
|Other Accession||P0C7V7, P42667, Q9R0P6, P67810, NP_055115.1|
|Predicted||Bovine, Mouse, Rat|
|Calculated MW||20625 Da|
|Antigen Region||95-123 aa|
|Other Names||Signal peptidase complex catalytic subunit SEC11A, Endopeptidase SP18, Microsomal signal peptidase 18 kDa subunit, SPase 18 kDa subunit, SEC11 homolog A, SEC11-like protein 1, SPC18, SEC11A, SEC11L1, SPC18, SPCS4A|
|Target/Specificity||This SC11A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-123 amino acids from the Central region of human SC11A.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SC11A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||SEC11L1, SPC18, SPCS4A|
|Function||Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.|
|Cellular Location||Microsome membrane; Single- pass type II membrane protein. Endoplasmic reticulum membrane; Single-pass type II membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Dodson, G., et al. Curr. Opin. Struct. Biol. 8(2):189-194(1998)
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