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DIRC2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q96SL1 |
| Other Accession | Q8BFQ6, NP_116228.1 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 52088 Da |
| Antigen Region | 202-229 aa |
| Gene ID | 84925 |
|---|---|
| Other Names | Disrupted in renal carcinoma protein 2, Disrupted in renal cancer protein 2, DIRC2 |
| Target/Specificity | This DIRC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-229 amino acids from the Central region of human DIRC2. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | DIRC2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SLC49A4 (HGNC:16628) |
|---|---|
| Function | Mediates H(+)-dependent pyridoxine transport. |
| Cellular Location | Lysosome membrane; Multi-pass membrane protein |
| Tissue Location | Ubiquitous. Expressed in proximal tubular cells of the kidney. Highly expressed in the placenta, brain and heart |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a membrane-bound protein from the major facilitator superfamily of transporters. Disruption of this gene by translocation has been associated with haplo-insufficiency and renal cell carcinomas. Alternatively spliced transcript variants have been described, but their biological validity has not yet been determined.
References
Bodmer, D., et al. Cancer Genet. Cytogenet. 136(2):95-100(2002)
Bodmer, D., et al. Hum. Mol. Genet. 11(6):641-649(2002)
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