|Application ||WB, E|
|Calculated MW||63616 Da|
|Antigen Region||501-528 aa|
|Other Names||Collagen alpha-3(IX) chain, COL9A3|
|Target/Specificity||This COL9A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 501-528 amino acids from the Central region of human COL9A3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||COL9A3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Structural component of hyaline cartilage and vitreous of the eye.|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes one of the three alpha chains of type IX collagen, the major collagen component of hyaline cartilage. Type IX collagen, a heterotrimeric molecule, is usually found in tissues containing type II collagen, a fibrillar collagen. Mutations in this gene are associated with multiple epiphyseal dysplasia type 3.
Jackson, G.C., et al. Am. J. Med. Genet. A 152A (4), 863-869 (2010) :
Videman, T., et al. Arthritis Rheum. 60(2):470-481(2009)
Karppinen, J., et al. Spine 33(11):1236-1241(2008)
Decramer, S., et al. World J Urol 25(5):457-465(2007)
Virtanen, I.M., et al. Spine 32(10):1129-1134(2007)
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