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POLDIP3 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

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  • IHC-P - POLDIP3 Antibody (N-term) AP20109a
    Immunohistochemical analysis of paraffin-embedded H. stomach section using POLDIP3 Antibody (N-term)(Cat#AP20109a). AP20109a was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.
  • IF - POLDIP3 Antibody (N-term) AP20109a
    Fluorescent image of Hela cells stained with POLDIP3 Antibody (N-term)(Cat#AP20109a). AP20109a was diluted at 1:25 dilution. An Alexa Fluor 488-conjugated goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody (green). Cytoplasmic actin was counterstained with Alexa Fluor® 555 conjugated with Phalloidin (red).
  • WB - POLDIP3 Antibody (N-term) AP20109a
    POLDIP3 Antibody (N-term) (Cat. #AP20109a) western blot analysis in Jurkat,mouse C2C12 cell line lysates (35ug/lane).This demonstrates the POLDIP3 Antibody antibody detected the POLDIP3 Antibody protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BY77
Other Accession Q8BG81, NP_115687.2
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 46089 Da
Antigen Region 93-120 aa
Additional Information
Gene ID 84271
Other Names Polymerase delta-interacting protein 3, 46 kDa DNA polymerase delta interaction protein, p46, S6K1 Aly/REF-like target, SKAR, POLDIP3, KIAA1649, PDIP46
Target/Specificity This POLDIP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-120 amino acids from the N-terminal region of human POLDIP3.
Dilution IHC-P~~1:25
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPOLDIP3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KIAA1649, PDIP46
Function Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. Involved in nuclear mRNA export; probably mediated by assoociation with the TREX complex.
Cellular Location Nucleus. Nucleus speckle. Cytoplasm. Note=Nucleocytoplasmic shuttling protein
Research Areas
Citations (0)

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This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit. This protein is a specific target of S6 kinase 1 and regulates cell growth. Two transcript variants that encode different protein isoforms have been identified. [provided by RefSeq].


Ma, X.M., et al. Cell 133(2):303-313(2008)
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Smyk, A., et al. FEBS J. 273(20):4728-4741(2006)
Andersen, J.S., et al. Nature 433(7021):77-83(2005)
Richardson, C.J., et al. Curr. Biol. 14(17):1540-1549(2004)

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$ 295.00
$ 99.00
Cat# AP20109a
(40 western blots)
Availability: In Stock
Bulk Size
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