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POPD3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9HBV1 |
| Other Accession | NP_071756.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 33870 Da |
| Antigen Region | 231-259 aa |
| Gene ID | 64208 |
|---|---|
| Other Names | Popeye domain-containing protein 3, Popeye protein 3, POPDC3, POP3 |
| Target/Specificity | This POPD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-259 amino acids from the C-terminal region of human POPD3. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | POPD3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | POPDC3 |
|---|---|
| Synonyms | POP3 |
| Function | May play a role in the maintenance of heart function mediated, at least in part, through cAMP-binding. May play a role in the regulation of KCNK2/TREK-1-mediated current amplitude (PubMed:31610034). |
| Cellular Location | Membrane; Multi-pass membrane protein |
| Tissue Location | Expressed predominantly in skeletal muscle (at protein level) (PubMed:10882522, PubMed:31610034). Also detected in heart (PubMed:10882522). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the POP family of proteins containing three putative transmembrane domains. This gene is expressed in cardiac and skeletal muscle and may play an important role in these tissues during development. Alternatively spliced transcript variants have been found.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Kim, M., et al. Carcinogenesis 31(9):1685-1693(2010)
Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Sulem, P., et al. Nat. Genet. 41(6):734-738(2009)
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