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SELM Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8WWX9 |
| Other Accession | NP_536355.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 16232 Da |
| Antigen Region | 117-145 aa |
| Gene ID | 140606 |
|---|---|
| Other Names | Selenoprotein M, SelM, SELM, SEPM |
| Target/Specificity | This SELM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 117-145 amino acids from the C-terminal region of human SELM. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SELM Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SELENOM {ECO:0000303|PubMed:27645994, ECO:0000312|HGNC:HGNC:30397} |
|---|---|
| Function | May function as a thiol-disulfide oxidoreductase that participates in disulfide bond formation. |
| Cellular Location | Cytoplasm, perinuclear region. Endoplasmic reticulum. Golgi apparatus. Note=Localized to perinuclear structures corresponding to Golgi and endoplasmic reticulum |
| Tissue Location | Widely expressed.. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This gene is expressed in a variety of tissues, and the protein is localized to the perinuclear structures. [provided by RefSeq].
References
Korotkov, K.V., et al. Mol. Cell. Biol. 22(5):1402-1411(2002)
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