|Application ||WB, E|
|Other Accession||Q9QUL6, P46460, P18708, NP_006169.2|
|Calculated MW||82594 Da|
|Antigen Region||668-696 aa|
|Other Names||Vesicle-fusing ATPase, N-ethylmaleimide-sensitive fusion protein, NEM-sensitive fusion protein, Vesicular-fusion protein NSF, NSF|
|Target/Specificity||This NSF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 668-696 amino acids from the C-terminal region of human NSF.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NSF Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling (By similarity).|
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Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seem to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.
Saus, E., et al. J Psychiatr Res 44(14):971-978(2010)
Hamza, T.H., et al. Nat. Genet. 42(9):781-785(2010)
Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Parashuraman, S., et al. FEBS Lett. 584(6):1251-1256(2010)
Simon-Sanchez, J., et al. Nat. Genet. 41(12):1308-1312(2009)
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