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ATP8B3 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ATP8B3 Antibody (N-term) AP20206A
    ATP8B3 Antibody (N-term) (Cat. #AP20206a) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the ATP8B3 antibody detected the ATP8B3 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O60423
Other Accession NP_620168.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 146752 Da
Antigen Region 56-84 aa
Additional Information
Gene ID 148229
Other Names Phospholipid-transporting ATPase IK, ATPase class I type 8B member 3, ATP8B3, ATP1K, FOS37502_2
Target/Specificity This ATP8B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-84 amino acids from the N-terminal region of human ATP8B3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsATP8B3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ATP8B3
Synonyms ATP1K, FOS37502_2
Function P4-ATPase flippase which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. May be responsible for the maintenance of asymmetric distribution of phosphatidylserine (PS) in spermatozoa membranes. Involved in acrosome reactions and binding of spermatozoa to zona pellucida (By similarity).
Cellular Location Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Multi-pass membrane protein. Endoplasmic reticulum
Tissue Location Isoform 3 was only detected in testis.
Research Areas
Citations (0)

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The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another. This gene encodes the member 3 of the phospholipid-transporting ATPase 8B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].


Scott, L.J., et al. Proc. Natl. Acad. Sci. U.S.A. 106(18):7501-7506(2009)
Harris, M.J., et al. Biochim. Biophys. Acta 1633(2):127-131(2003)
Halleck, M.S., et al. Physiol. Genomics 1(3):139-150(1999)
Fries, A.S., et al. Lab. Anim. 12(1):1-4(1978)

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$ 295.00
$ 99.00
Cat# AP20206A
(40 western blots)
Availability: In Stock
Bulk Size
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