|Application ||WB, E|
|Calculated MW||36694 Da|
|Antigen Region||116-144 aa|
|Other Names||Probable tRNA pseudouridine synthase 2, 5499-, TRUB2|
|Target/Specificity||This TRUB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-144 amino acids from the Central region of human TRUB2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TRUB2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be responsible for synthesis of pseudouridine from uracil in transfer RNAs.|
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Provided below are standard protocols that you may find useful for product applications.
Pseudouridine is an abundant component of rRNAs and tRNAs and is enzymatically generated by isomerization of uridine by pseudouridine synthase (Zucchini et al., 2003 [PubMed 12736709]).
Humphray, S.J., et al. Nature 429(6990):369-374(2004)
Zucchini, C., et al. Int. J. Mol. Med. 11(6):697-704(2003)
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