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ANO6 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

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  • WB - ANO6 Antibody (N-term) AP20252a
    ANO6 Antibody (N-term) (Cat. #AP20252a) western blot analysis in SW480 cell line lysates (35ug/lane).This demonstrates the ANO6 antibody detected the ANO6 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q4KMQ2
Other Accession NP_001020527.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 106165 Da
Antigen Region 68-96 aa
Additional Information
Gene ID 196527
Other Names Anoctamin-6, Small-conductance calcium-activated nonselective cation channel, SCAN channel, Transmembrane protein 16F, ANO6, TMEM16F
Target/Specificity This ANO6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-96 amino acids from the N-terminal region of human ANO6.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsANO6 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ANO6
Synonyms TMEM16F
Function Small-conductance calcium-activated nonselective cation (SCAN) channel which acts as a regulator of phospholipid scrambling in platelets and osteoblasts. Phospholipid scrambling results in surface exposure of phosphatidylserine which in platelets is essential to trigger the clotting system whereas in osteoblasts is essential for the deposition of hydroxyapatite during bone mineralization. Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Can generate outwardly rectifying chloride channel currents in airway epithelial cells and Jurkat T lymphocytes.
Cellular Location Cell membrane; Multi-pass membrane protein Note=Shows an intracellular localization according to PubMed:22075693
Tissue Location Expressed in embryonic stem cell, fetal liver, retina, chronic myologenous leukemia and intestinal cancer
Research Areas
Citations (0)

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May act as a calcium-activated chloride channel.


Rose, J. Phd, et al. Mol. Med. (2010) In press :
Hartzell, H.C., et al. J. Physiol. (Lond.) 587 (PT 10), 2127-2139 (2009) :
Katoh, M., et al. Int. J. Oncol. 24(5):1345-1349(2004)
Adams, M.D., et al. Nature 377 (6547 SUPPL), 3-174 (1995) :

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$ 295.00
$ 99.00
Cat# AP20252a
(40 western blots)
Availability: In Stock
Bulk Size
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