|Application ||WB, E|
|Calculated MW||19194 Da|
|Antigen Region||26-55 aa|
|Other Names||Peptidyl-tRNA hydrolase 2, mitochondrial, PTH 2, Bcl-2 inhibitor of transcription 1, PTRH2, BIT1, PTH2|
|Target/Specificity||This PTRH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human PTRH2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PTRH2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis.|
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Provided below are standard protocols that you may find useful for product applications.
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis (By similarity). Promotes caspase-independent apoptosis by regulating the function of two transcriptional regulators, AES and TLE1.
Fan, T., et al. Int. J. Oncol. 35(2):359-367(2009)
Biliran, H., et al. J. Biol. Chem. 283(42):28029-28037(2008)
Bouchentouf, M., et al. Am. J. Transplant. 7(6):1491-1505(2007)
Jan, Y., et al. Cell 116(5):751-762(2004)
De Pereda, J.M., et al. J. Biol. Chem. 279(9):8111-8115(2004)
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