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POLR2H Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P52434 |
| Other Accession | Q923G2, NP_006223.2, F2Z4H3 |
| Reactivity | Human |
| Predicted | Bovine, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 17143 Da |
| Antigen Region | 59-87 aa |
| Gene ID | 5437 |
|---|---|
| Other Names | DNA-directed RNA polymerases I, II, and III subunit RPABC3, RNA polymerases I, II, and III subunit ABC3, DNA-directed RNA polymerase II subunit H, DNA-directed RNA polymerases I, II, and III 171 kDa polypeptide, RPB17, RPB8 homolog, hRPB8, POLR2H |
| Target/Specificity | This POLR2H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-87 amino acids from the Central region of human POLR2H. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | POLR2H Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | POLR2H (HGNC:9195) |
|---|---|
| Function | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. |
| Cellular Location | Nucleus {ECO:0000269|PubMed:33335104, ECO:0000269|PubMed:9852112, ECO:0000269|Ref.6}. Nucleus, nucleolus |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes one of the essential subunits of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III.
References
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Michiels, S., et al. Carcinogenesis 30(5):763-768(2009)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Kang, X., et al. J. Biol. Chem. 281(26):18216-18226(2006)
Andersen, J.S., et al. Nature 433(7021):77-83(2005)
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