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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   FMO5 Antibody (C-term)   

FMO5 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - FMO5 Antibody (C-term) AP20282B
    FMO5 Antibody (C-term) (Cat. #AP20282b) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the FMO5 antibody detected the FMO5 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P49326
Other Accession NP_001452.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 60221 Da
Antigen Region 474-502 aa
Additional Information
Gene ID 2330
Other Names Dimethylaniline monooxygenase [N-oxide-forming] 5, Dimethylaniline oxidase 5, Hepatic flavin-containing monooxygenase 5, FMO 5, FMO5
Target/Specificity This FMO5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474-502 amino acids from the C-terminal region of human FMO5.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFMO5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FMO5
Function In contrast with other forms of FMO it does not seem to be a drug-metabolizing enzyme.
Cellular Location Microsome membrane. Endoplasmic reticulum membrane
Tissue Location Expressed in fetal and adult liver.
Research Areas
Citations (0)

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Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants.


Rose, J. Phd, et al. Mol. Med. (2010) In press :
Ross, C.J., et al. Nat. Genet. 41(12):1345-1349(2009)
Wheeler, H.E., et al. PLoS Genet. 5 (10), E1000685 (2009) :
Zhang, J., et al. Drug Metab. Dispos. 34(1):19-26(2006)
Furnes, B., et al. Drug Metab. Dispos. 31(2):187-193(2003)

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$ 295.00
$ 99.00
Cat# AP20282B
(40 western blots)
Availability: In Stock
Bulk Size
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