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EDC3 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - EDC3 Antibody (Center) AP20283c
    EDC3 Antibody (Center) (Cat. #AP20283c) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the EDC3 antibody detected the EDC3 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96F86
Other Accession Q4R8V9, NP_079359.2
Reactivity Human
Predicted Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 56078 Da
Antigen Region 219-247 aa
Additional Information
Gene ID 80153
Other Names Enhancer of mRNA-decapping protein 3, LSM16 homolog, YjeF N-terminal domain-containing protein 2, YjeF_N2, hYjeF_N2, YjeF domain-containing protein 1, EDC3, LSM16, YJDC, YJEFN2
Target/Specificity This EDC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 219-247 amino acids from the Central region of human EDC3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsEDC3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EDC3
Synonyms LSM16, YJDC, YJEFN2
Function Binds single-stranded RNA. In the process of mRNA degradation, may play a role in mRNA decapping. May play a role in spermiogenesis and oogenesis.
Cellular Location Cytoplasm, P-body. Note=Processing bodies (PB)
Tissue Location Expressed in theca and granulosa cells in ovary, and in spermatids of the meiotic division part II and apical membrane of Sertoli cells in testis (at protein level) Also expressed in brain and mammary gland
Citations (0)

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EDC3 is associated with an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).


Tritschler, F., et al. Mol. Cell 33(5):661-668(2009)
Ling, S.H., et al. Mol. Cell. Biol. 28(19):5965-5976(2008)
Tritschler, F., et al. Mol. Cell. Biol. 27(24):8600-8611(2007)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Rudolph, C., et al. Horm. Metab. Res. 39(5):322-335(2007)

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$ 295.00
$ 99.00
Cat# AP20283c
(40 western blots)
Availability: In Stock
Bulk Size
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