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KCNMB2 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - KCNMB2 Antibody (N-term) AP20284a
    KCNMB2 Antibody (N-term) (Cat. #AP20284a) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the KCNMB2 antibody detected the KCNMB2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y691
Other Accession Q811Q0, NP_852006.1
Reactivity Human
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 27130 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 10242
Other Names Calcium-activated potassium channel subunit beta-2, BK channel subunit beta-2, BKbeta2, Hbeta2, Calcium-activated potassium channel, subfamily M subunit beta-2, Charybdotoxin receptor subunit beta-2, Hbeta3, K(VCA)beta-2, Maxi K channel subunit beta-2, Slo-beta-2, KCNMB2
Target/Specificity This KCNMB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human KCNMB2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKCNMB2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons.
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Expressed in kidney, heart and brain. Highly expressed in ovary. Expressed at low level in other tissues
Research Areas
Citations (0)

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MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Two variants encoding the same protein have been found for this gene. [provided by RefSeq].


Trevino, L.R., et al. Nat. Genet. 41(9):1001-1005(2009)
Lee, U.S., et al. J. Physiol. (Lond.) 587 (PT 7), 1481-1498 (2009) :
Zarei, M.M., et al. Neuroscience 147(1):80-89(2007)
Zeng, X.H., et al. J. Neurosci. 27(17):4707-4715(2007)
Orio, P., et al. J. Gen. Physiol. 127(2):191-204(2006)

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$ 295.00
$ 99.00
Cat# AP20284a
(40 western blots)
Availability: In Stock
Bulk Size
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