|Application ||WB, E|
|Calculated MW||35386 Da|
|Antigen Region||70-98 aa|
|Other Names||Ret finger protein-like 3, RFPL3|
|Target/Specificity||This RFPL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-98 amino acids from the N-terminal region of human RFPL3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RFPL3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||(Microbial infection) Stimulates the activity of Human Immunodeficiency Virus 1/HIV-1 pre-integration complex.|
|Cellular Location||Cytoplasm. Nucleus. Note=A higher concentration of RFPL3 is observed in the cytoplasm compared to the nucleus|
|Tissue Location||Expressed during neurogenesis in differentiating human embryonic stem cells and in the developing human neocortex.|
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Provided below are standard protocols that you may find useful for product applications.
The function of this protein remains unknown. RFPL3 protein is encoded by 2 exons and is 91 to 94% identical to RFPL1 and RFPL2. Exon 1 of RFPL3 encodes a putative RING-like motif, and exon 2 encodes a B30-2 domain. Seroussi et al. (1999) proposed that RFPL3 arose from an intrachromosomal duplication.
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