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Mouse Mast1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9R1L5 |
| Other Accession | Q810W7 |
| Reactivity | Mouse |
| Predicted | Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 170997 Da |
| Antigen Region | 1438-1464 aa |
| Gene ID | 56527 |
|---|---|
| Other Names | Microtubule-associated serine/threonine-protein kinase 1, Syntrophin-associated serine/threonine-protein kinase, Mast1 {ECO:0000312|MGI:MGI:1861901} |
| Target/Specificity | This Mouse Mast1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1438-1464 amino acids from the C-terminal region of mouse Mast1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Mouse Mast1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Mast1 {ECO:0000312|MGI:MGI:1861901} |
|---|---|
| Function | Microtubule-associated protein essential for correct brain development (PubMed:30449657). Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. |
| Cellular Location | Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite. Note=Also localized in the soma of neurons (PubMed:30449657). Observed as punctate clusters in the processes of interneurons and along the cell body periphery Colocalizes with syntrophins at the cell membrane |
| Tissue Location | Expressed in the brain (PubMed:30449657). Expressed in the developing cortical plate, the intermediate zone and corpus callosal fibers that cross the midline (PubMed:30449657). Detected at low levels in the testis, liver and spleen (PubMed:30449657). Expressed in proximity to neuronal nuclei throughout the cortex and cerebellum, and in the vascular endothelium. Also detected in ependymal cells, the choroid plexus, and in developing spermatid acrosomes |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins.
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$ 182.50
$ 70.00
Cat# AP20323b
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