APBB2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q92870 |
Other Accession | Q9DBR4 |
Reactivity | Human |
Predicted | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 83374 Da |
Antigen Region | 216-244 aa |
Gene ID | 323 |
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Other Names | Amyloid beta A4 precursor protein-binding family B member 2, Protein Fe65-like 1, APBB2, FE65L, FE65L1 |
Target/Specificity | This APBB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 216-244 amino acids from the Central region of human APBB2. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | APBB2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | APBB2 (HGNC:582) |
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Function | Plays a role in the maintenance of lens transparency, and may also play a role in muscle cell strength (By similarity). Involved in hippocampal neurite branching and neuromuscular junction formation, as a result plays a role in spatial memory functioning (By similarity). Activates transcription of APP (PubMed:14527950). |
Cellular Location | Endoplasmic reticulum. Golgi apparatus. Early endosome |
Tissue Location | Widely expressed.. |
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Provided below are standard protocols that you may find useful for product applications.
Background
May modulate the internalization of beta-amyloid precursor protein.
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