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>   home   >   Products   >   Primary Antibodies   >   ESCO1 Antibody (C-term)   

ESCO1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - ESCO1 Antibody (C-term) AP20370b
    ESCO1 Antibody (C-term) (Cat. #AP20370b) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the ESCO1 antibody detected the ESCO1 protein (arrow).
  • WB - ESCO1 Antibody (C-term) AP20370b
    ESCO1 Antibody (C-term) (Cat. #AP20370b) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the ESCO1 antibody detected the ESCO1 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q5FWF5
Other Accession Q69Z69
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 94983 Da
Antigen Region 661-687 aa
Additional Information
Gene ID 114799
Other Names N-acetyltransferase ESCO1, 231-, CTF7 homolog 1, Establishment factor-like protein 1, EFO1p, hEFO1, Establishment of cohesion 1 homolog 1, ECO1 homolog 1, ESO1 homolog 1, ESCO1, EFO1, KIAA1911
Target/Specificity This ESCO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 661-687 amino acids from the C-terminal region of human ESCO1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsESCO1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ESCO1
Synonyms EFO1, KIAA1911
Function Acetyltransferase required for the establishment of sister chromatid cohesion and couple the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase. Acts by mediating the acetylation of cohesin component SMC3.
Cellular Location Nucleus. Chromosome. Note=Nuclear at interphase, associated with chromosomes during mitosis
Tissue Location Widely expressed. Expressed in heart, brain, liver, placenta, lung, kidney and pancreas. Highly expressed in muscle.
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Background

Acetyltransferase required for the establishment of sister chromatid cohesion and couple the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase. Acts by mediating the acetylation of cohesin component SMC3.

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Cat# AP20370b
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(40 western blots)
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