|Application ||WB, E|
|Calculated MW||15789 Da|
|Antigen Region||105-131 aa|
|Other Names||Proteasome maturation protein, Proteassemblin, Protein UMP1 homolog, hUMP1, Voltage-gated K channel beta subunit 41, POMP, C13orf12, UMP1|
|Target/Specificity||This POMP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 105-131 amino acids from the C-terminal region of human POMP.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||POMP Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Molecular chaperone essential for the assembly of standard proteasomes and immunoproteasomes. Degraded after completion of proteasome maturation. Mediates the association of 20S preproteasome with the endoplasmic reticulum.|
|Cellular Location||Cytoplasm, cytosol. Nucleus. Microsome membrane|
|Tissue Location||Strongly expressed from the basal layer to the granular layer of healthy epidermis, whereas in KLICK patients there is a gradual decrease of expression toward the granular layer.|
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Molecular chaperone essential for the assembly of standard proteasomes and immunoproteasomes. Degraded after completion of proteasome maturation. Mediates the association of 20S preproteasome with the endoplasmic reticulum.
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