|Application ||WB, E|
|Calculated MW||40982 Da|
|Antigen Region||196-224 aa|
|Other Names||G-protein coupled receptor 4, G-protein coupled receptor 19, GPR4, GPR19|
|Target/Specificity||This GPR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-224 amino acids from the Central region of human GPR4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GPR4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Proton-sensing receptor coupled to several G-proteins, including G(s), G(13) and G(q)/G(11) proteins, leading to cAMP production.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
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Provided below are standard protocols that you may find useful for product applications.
Proton-sensing receptor coupled to several G-proteins, including G(s), G(13) and G(q)/G(11) proteins, leading to cAMP production.
Heiber M., et al. DNA Cell Biol. 14:25-35(1995).
Mahadevan M.S., et al. Genomics 30:84-88(1995).
An S., et al. FEBS Lett. 375:121-124(1995).
Kaighin V.A., et al. Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
Ota T., et al. Nat. Genet. 36:40-45(2004).
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