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GRN Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

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  • IHC-P - GRN Antibody (C-term) AP20450b
    Immunohistochemical analysis of paraffin-embedded H. kidney section using GRN Antibody (C-term)(Cat#AP20450b). AP20450b was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.
  • WB - GRN Antibody (C-term) AP20450b
    GRN Antibody (C-term) (Cat. #AP20450b) western blot analysis in A2058,HepG2,HL-60,T47D cell line lysates (35ug/lane).This demonstrates the GRN antibody detected the GRN protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P28799
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 63544 Da
Antigen Region 563-591 aa
Additional Information
Gene ID 2896
Other Names Granulins, Proepithelin, PEPI, Acrogranin, Glycoprotein of 88 Kda, Progranulin, Paragranulin, Granulin-1, Granulin G, Granulin-2, Granulin F, Granulin-3, Granulin B, Granulin-4, Granulin A, Granulin-5, Granulin C, Granulin-6, Granulin D, Granulin-7, Granulin E, GRN
Target/Specificity This GRN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 563-591 amino acids from the C-terminal region of human GRN.
Dilution IHC-P~~1:25
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGRN Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GRN
Function Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling.
Cellular Location Secreted.
Tissue Location In myelogenous leukemic cell lines of promonocytic, promyelocytic, and proerythroid lineage, in fibroblasts, and very strongly in epithelial cell lines. Present in inflammatory cells and bone marrow. Highest levels in kidney
Research Areas
Citations (0)

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Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling. Granulin-4 promotes proliferation of the epithelial cell line A431 in culture while granulin-3 acts as an antagonist to granulin-4, inhibiting the growth.


Bhandari V., et al. Biochem. Biophys. Res. Commun. 188:57-63(1992).
Plowman G.D., et al. J. Biol. Chem. 267:13073-13078(1992).
Bhandari V., et al. Proc. Natl. Acad. Sci. U.S.A. 89:1715-1719(1992).
Lu R., et al. Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases.
Yu W., et al. Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.

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$ 295.00
$ 99.00
Cat# AP20450b
(40 western blots)
Availability: In Stock
Bulk Size
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