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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SOX4 Antibody (N-term)   

SOX4 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SOX4 Antibody (N-term) AP2045A
    Western blot analysis of SOX4 antibody (N-term) (Cat. #AP2045a) in A2058 cell line lysates (35ug/lane). SOX4 (arrow) was detected using the purified Pab.
  • IHC-P - SOX4 Antibody (N-term) AP2045A
    Formalin-fixed and paraffin-embedded human brain reacted with SOX4 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - SOX4 Antibody (N-term) AP2045A
    SOX4 Antibody (N-term) (Cat. #AP2045a) flow cytometric analysis of A2058 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
  • IF - SOX4 Antibody (N-term) AP2045A
    Fluorescent confocal image of Hela cell stained with SOX4 Antibody (N-term)(Cat#AP2045a).Hela cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with SOX4 primary antibody (1:25, 1 h at 37℃). For secondary antibody, Alexa Fluor® 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37℃).Cytoplasmic actin was counterstained with Alexa Fluor® 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37℃). Nuclei were counterstained with DAPI (blue) (10 µg/ml, 10 min). SOX4 immunoreactivity is localized to Mitochondria significantly and Nucleus weakly.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q06945
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 47263 Da
Antigen Region 86-114 aa
Additional Information
Gene ID 6659
Other Names Transcription factor SOX-4, SOX4
Target/Specificity This SOX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-114 amino acids from the N-terminal region of human SOX4.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSOX4 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SOX4
Function Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267, ECO:0000269|PubMed:16631117}
Tissue Location Testis, brain, and heart.
Research Areas
Citations ( 0 )


SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.


Farr C.J., Easty D.J.Mamm. Genome 4:577-584(1993)
Pan X., Li H., Zhang P.Biochem. Biophys. Res. Commun. 344:727-734(2006)

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$ 295.00
$ 99.00
Cat# AP2045A
(40 western blots)
Availability: In Stock
Bulk Size
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