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SOX4 Antibody (Center)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP2045c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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SOX4 Antibody (Center) - Product info | |
| Application | WB, IHC
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| Primary Accession | Q06945 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 47263 Da |
SOX4 Antibody (Center) - Additional info | |
| Gene ID 6659 | |
| Other Names SOX4; Transcription factor SOX-4 | |
| Target/Specificity This SOX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276~305 amino acids from the Center region of human SOX4. | |
| Dilution WB~~1:50~100WB~~1:1000 IHC~~1:50~100 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions SOX4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
SOX4 Antibody (Center) - Protein Information | |
| Name SOX4 | |
| Function Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif | |
| Cellular Location Nucleus. | |
| Tissue Location Testis, brain, and heart. | |
SOX4 Antibody (Center) - Related products
AP2045a: SOX4 Antibody (N-term)
AP2045c: SOX4 Antibody (Center)
BP2045a: SOX4 Antibody (N-term) Blocking Peptide
SOX4 Antibody (Center) - Application data
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Western blot analysis of SOX4 Antibody (Center) (Cat.#AP2045c) in 293, CEM, Jurkat, Y79 cell line lysates (35ug/lane). SOX4 (arrow) was detected using the purified Pab.
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Formalin-fixed and paraffin-embedded human brain reacted with SOX4 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
SOX4 Antibody (Center) - Research Areas
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BACKGROUND
SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.
REFERENCES
Farr C.J., Easty D.J.Mamm. Genome 4:577-584(1993) Pan X., Li H., Zhang P.Biochem. Biophys. Res. Commun. 344:727-734(2006)
