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NTN1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - NTN1 Antibody (C-term) AP20462b
    NTN1 Antibody (C-term) (Cat. #AP20462b) western blot analysis in U87-MG cell line lysates (35ug/lane).This demonstrates the NTN1 antibody detected the NTN1 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O95631
Other Accession Q2HXW4, O09118, Q90922
Reactivity Human
Predicted Chicken, Mouse, Pig
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 67748 Da
Antigen Region 568-596 aa
Additional Information
Gene ID 9423
Other Names Netrin-1, Epididymis tissue protein Li 131P, NTN1, NTN1L
Target/Specificity This NTN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 568-596 amino acids from the C-terminal region of human NTN1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNTN1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NTN1
Synonyms NTN1L
Function Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Widely expressed in normal adult tissues with highest levels in heart, small intestine, colon, liver and prostate. Reduced expression in brain tumors and neuroblastomas Expressed in epididymis (at protein level)
Research Areas
Citations (0)

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Background

Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.

References

Meyerhardt J.A., et al. Cell Growth Differ. 10:35-42(1999).
Zody M.C., et al. Nature 440:1045-1049(2006).
Li J., et al. Mol. Cell. Proteomics 9:2517-2528(2010).
Mazelin L., et al. Nature 431:80-84(2004).
Liu G., et al. Proc. Natl. Acad. Sci. U.S.A. 106:2951-2956(2009).

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$ 295.00
$ 99.00
Cat# AP20462b
Size:
Quantity:
(40 western blots)
Availability: In Stock
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