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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CNO Antibody (Center)   

CNO Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CNO Antibody (Center) AP20464c
    CNO Antibody (Center) (Cat. #AP20464c) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the CNO antibody detected the CNO protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NUP1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 23351 Da
Antigen Region 114-143 aa
Additional Information
Gene ID 55330
Other Names Biogenesis of lysosome-related organelles complex 1 subunit 4, BLOC-1 subunit 4, Protein cappuccino homolog, BLOC1S4, CNO
Target/Specificity This CNO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-143 amino acids from the Central region of human CNO.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCNO Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BLOC1S4
Synonyms CNO
Function Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking.
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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The BLOC-1 complex is required for normal biogenesis of lysosome-related organelles, such as platelet dense granules and melanosomes. Plays a role in intracellular vesicle trafficking (By similarity).


Ota T., et al. Nat. Genet. 36:40-45(2004).
Hillier L.W., et al. Nature 434:724-731(2005).

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$ 295.00
$ 99.00
Cat# AP20464c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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