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CRIPTO (TDGF1) Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CRIPTO (TDGF1) Antibody (N-term) AP2047a
    Western blot analysis of CRIPTO (TDGF1) Antibody (N-term) (Cat. #AP2047a) in Jurkat cell line lysates (35ug/lane). TDGF1 (arrow) was detected using the purified Pab.
  • IHC-P - CRIPTO (TDGF1) Antibody (N-term) AP2047a
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P13385
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 21169 Da
Antigen Region 18-48 aa
Additional Information
Gene ID 6997
Other Names Teratocarcinoma-derived growth factor 1, Cripto-1 growth factor, CRGF, Epidermal growth factor-like cripto protein CR1, TDGF1, CRIPTO
Target/Specificity This CRIPTO (TDGF1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-48 amino acids from the N-terminal region of human CRIPTO (TDGF1).
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCRIPTO (TDGF1) Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TDGF1
Synonyms CRIPTO
Function Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor
Tissue Location Preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts. Expressed in breast and lung.
Research Areas
Citations (0)

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TDGF1 is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers. This protein could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. It is preferentially expressed in gastric and colorectal carcinomas compared to their normal counterparts.


Parisi, S., et al., J. Cell Biol. 163(2):303-314 (2003).
Gray, P.C., et al., Proc. Natl. Acad. Sci. U.S.A. 100(9):5193-5198 (2003).
Yan, Y.T., et al., Mol. Cell. Biol. 22(13):4439-4449 (2002).
de la Cruz, J.M., et al., Hum. Genet. 110(5):422-428 (2002).
Dono, R., et al., Am. J. Hum. Genet. 49(3):555-565 (1991).

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Cat# AP2047a
(40 western blots)
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