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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   GBP2 Antibody (Center)   

GBP2 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

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  • WB - GBP2 Antibody (Center) AP20488c
    GBP2 Antibody (Center) (Cat. #AP20488c) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the GBP2 antibody detected the GBP2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P32456
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 67209 Da
Antigen Region 192-220 aa
Additional Information
Gene ID 2634
Other Names Interferon-induced guanylate-binding protein 2, GTP-binding protein 2, GBP-2, HuGBP-2, Guanine nucleotide-binding protein 2, GBP2
Target/Specificity This GBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-220 amino acids from the Central region of human GBP2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGBP2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GBP2
Function Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity).
Cellular Location Cytoplasm. Nucleus. Golgi apparatus membrane; Lipid-anchor
Research Areas
Citations (0)

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Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product.


Cheng Y.-S.E., et al. Mol. Cell. Biol. 11:4717-4725(1991).
Schwemmle M., et al. Submitted (SEP-1991) to the EMBL/GenBank/DDBJ databases.
Bechtel S., et al. BMC Genomics 8:399-399(2007).
Ota T., et al. Nat. Genet. 36:40-45(2004).
Ebert L., et al. Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.

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$ 295.00
$ 99.00
Cat# AP20488c
(40 western blots)
Availability: In Stock
Bulk Size
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