|Application ||WB, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||28600 Da|
|Antigen Region||161-189 aa|
|Other Names||CCAAT/enhancer-binding protein delta, C/EBP delta, Transcription factor CELF, Cebpd, Celf|
|Target/Specificity||This Rat Cebpd antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-189 amino acids from the Central region of rat Cebpd.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||R Cebpd Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription activator that recognizes two different DNA motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers (PubMed:1714459). Important transcription factor regulating the expression of genes involved in immune and inflammatory responses. Transcriptional activator that enhances IL6 transcription alone and as heterodimer with CEBPB (By similarity).|
|Tissue Location||Ubiquitously expressed.|
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Provided below are standard protocols that you may find useful for product applications.
C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages (By similarity).
Kageyama R., et al. J. Biol. Chem. 266:15525-15531(1991).
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