|Application ||WB, IHC-P, E|
|Other Accession||Q7ZYD5, Q8K3P6, A2ASZ8, Q0V7M4, A2CEQ0|
|Predicted||Zebrafish, Bovine, Mouse, Xenopus|
|Calculated MW||52663 Da|
|Antigen Region||63-93 aa|
|Other Names||Calcium-binding mitochondrial carrier protein SCaMC-2, Mitochondrial ATP-Mg/Pi carrier protein 3, Mitochondrial Ca(2+)-dependent solute carrier protein 3, Small calcium-binding mitochondrial carrier protein 2, Solute carrier family 25 member 25, SLC25A25, APC3, KIAA1896, MCSC3, SCAMC2|
|Target/Specificity||This SLC25A25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-93 amino acids from the N-terminal region of human SLC25A25.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SLC25A25 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||APC3, KIAA1896, MCSC3, SCAMC2|
|Function||Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria.|
|Cellular Location||Mitochondrion inner membrane; Multi- pass membrane protein|
|Tissue Location||Present in various cell lines (at protein level). Widely expressed. Expressed in fetal and adult liver, skeletal muscle, testis, ovary, hippocampus and caudate nucleus Isoform 1 is present in all tissues tested. Isoform 2 expression is restricted to kidney and lung.|
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Provided below are standard protocols that you may find useful for product applications.
Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria.
del Arco A., et al. J. Biol. Chem. 279:24701-24713(2004).
Fiermonte G., et al. J. Biol. Chem. 279:30722-30730(2004).
Nagase T., et al. DNA Res. 8:179-187(2001).
Clark H.F., et al. Genome Res. 13:2265-2270(2003).
Ota T., et al. Nat. Genet. 36:40-45(2004).
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