|Application ||WB, E|
|Calculated MW||47380 Da|
|Antigen Region||200-230 aa|
|Other Names||SH2 domain-containing protein 5, Sh2d5|
|Target/Specificity||This Mouse Sh2d5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-230 amino acids from the Central region of mouse Sh2d5.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||M Sh2d5 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in synaptic plasticity regulation through the control of Rac-GTP levels.|
|Cellular Location||Cell junction, synapse, postsynaptic cell membrane, postsynaptic density|
|Tissue Location||Highly expressed in brain, particularly in Purkinjie cells in the cerebellum and the cornu ammonis of the hippocampus.|
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Provided below are standard protocols that you may find useful for product applications.
The function of this protein is unknown.
Trinidad J.C., et al. Mol. Cell. Proteomics 5:914-922(2006).
Munton R.P., et al. Mol. Cell. Proteomics 6:283-293(2007).
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