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M Tfap2c Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - M Tfap2c Antibody (N-term) AP20531a
    Mouse Tfap2c Antibody (N-term) (Cat. #AP20531a) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Mouse Tfap2c antibody detected the Mouse Tfap2c protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q61312
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 49137 Da
Antigen Region 123-144 aa
Additional Information
Gene ID 21420
Other Names Transcription factor AP-2 gamma, AP2-gamma, AP-22, Activating enhancer-binding protein 2 gamma, Tfap2c, Tcfap2c
Target/Specificity This Mouse Tfap2c antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-144 amino acids from the N-terminal region of Mouse Tfap2c.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsM Tfap2c Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Tfap2c
Synonyms Tcfap2c
Function Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.
Cellular Location Nucleus.
Tissue Location Expressed in lung, ovary and testis. Expressed in most squamous epithelia. Also, detected in several exocrine glands including the prostate, the preputial and salivary glands, serous glands of the tongue and ocular harderian glands
Research Areas
Citations (0)

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Background

Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.

References

Oulad-Abdelghani M., et al. Exp. Cell Res. 225:338-347(1996).
Carninci P., et al. Science 309:1559-1563(2005).
Church D.M., et al. PLoS Biol. 7:E1000112-E1000112(2009).
Mural R.J., et al. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Yahata T., et al. Genomics 80:601-613(2002).

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$ 295.00
$ 99.00
Cat# AP20531a
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
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