|Application ||WB, IHC-P, E|
|Calculated MW||81609 Da|
|Other Names||Zinc finger protein 175, Zinc finger protein OTK18, ZNF175|
|Target/Specificity||This ZNF175 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 150-187 amino acids from the N-terminal region of human ZNF175.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ZNF175 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Down-regulates the expression of several chemokine receptors. Interferes with HIV-1 replication by suppressing Tat- induced viral LTR promoter activity.|
|Cellular Location||Cytoplasm. Nucleus.|
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Down-regulates the expression of several chemokine receptors. Interferes with HIV-1 replication by suppressing Tat- induced viral LTR promoter activity.
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Grimwood J.,et al.Nature 428:529-535(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Carlson K.A.,et al.J. Immunol. 172:381-391(2004).
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