|Application ||WB, E|
|Other Accession||Q61012, P02698|
|Calculated MW||8496 Da|
|Other Names||Guanine nucleotide-binding protein G(T) subunit gamma-T1, Transducin gamma chain, GNGT1|
|Target/Specificity||This GNGT1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 56-91 amino acids from the C-terminal region of human GNGT1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GNGT1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.|
|Cellular Location||Cell membrane; Lipid-anchor; Cytoplasmic side|
|Tissue Location||Retinal rod outer segment.|
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Provided below are standard protocols that you may find useful for product applications.
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.
Tao L.,et al.Exp. Eye Res. 56:497-507(1993).
Scherer S.W.,et al.Genomics 35:241-243(1996).
Puhl H.L. III,et al.Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Scherer S.W.,et al.Science 300:767-772(2003).
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