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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   IL8RB Antibody (N-term)   

IL8RB Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - IL8RB Antibody (N-term) AP20651a
    Western blot analysis of lysates from HL-60, KG-1, THP-1, U-937 cell line , human spleen and lung tissue lysate(from left to right), using IL8RB Antibody (N-term)(Cat. #AP20651a). AP20651a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P25025
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 40759 Da
Additional Information
Gene ID 3579
Other Names C-X-C chemokine receptor type 2, CXC-R2, CXCR-2, CDw128b, GRO/MGSA receptor, High affinity interleukin-8 receptor B, IL-8R B, IL-8 receptor type 2, CD182, CXCR2, IL8RB
Target/Specificity This IL8RB antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 7-38 amino acids from the N-terminal region of human IL8RB.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIL8RB Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CXCR2
Synonyms IL8RB
Function Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Cellular Location Cell membrane; Multi-pass membrane protein.
Research Areas
Citations (0)

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Background

Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.

References

Murphy P.M.,et al.Science 253:1280-1283(1991).
Cerretti D.P.,et al.Mol. Immunol. 30:359-367(1993).
Sprenger H.,et al.J. Biol. Chem. 269:11065-11072(1994).
Ahuja S.K.,et al.J. Biol. Chem. 269:26381-26389(1994).
Kato H.,et al.Genes Immun. 1:330-337(2000).

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$ 295.00
$ 99.00
Cat# AP20651a
Size:
Quantity:
(40 western blots)
Availability: In Stock
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