|Application ||WB, E|
|Other Names||Fetal and adult testis-expressed transcript protein, Cancer/testis antigen 43, CT43, Tumor antigen BJ-HCC-2, FATE1, FATE|
|Target/Specificity||This FATE1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 107-140 amino acids from the Central region of human FATE1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FATE1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Membrane; Single-pass membrane protein|
|Tissue Location||Testis-specific in fetus (aged from 6 to 11 weeks). In adult, expressed predominantly in testis, with some expression in lung, heart, kidney, adrenal gland and whole brain EMBL; AF249872; AAK69024.1; -; mRNA EMBL; AY101182; AAM48744.1; -; mRNA EMBL; AK057369; BAB71454.1; -; mRNA EMBL; BC022064; AAH22064.1; -; mRNA CCDS; CCDS14700.1; - RefSeq; NP_149076.1; NM_033085.2 UniGene; Hs.301960; - ProteinModelPortal; Q969F0; - SMR; Q969F0; - BioGrid; 124636; 54 IntAct; Q969F0; 90 MINT; MINT-1474102; - STRING; 9606.ENSP00000359375; - BioMuta; FATE1; - DMDM; 37078481; - PaxDb; Q969F0; - PeptideAtlas; Q969F0; - PRIDE; Q969F0; - DNASU; 89885; - Ensembl; ENST00000370350; ENSP00000359375; ENSG00000147378 GeneID; 89885; - KEGG; hsa:89885; - UCSC; uc004fex.4; human CTD; 89885; - DisGeNET; 89885; - GeneCards; FATE1; - HGNC; HGNC:24683; FATE1 HPA; HPA034604; - MIM; 300450; gene neXtProt; NX_Q969F0; - OpenTargets; ENSG00000147378; - PharmGKB; PA134875203; - eggNOG; ENOG410J190; Eukaryota eggNOG; ENOG410YXUY; LUCA GeneTree; ENSGT00390000006832; - HOGENOM; HOG000293282; - HOVERGEN; HBG051556; - InParanoid; Q969F0; - OMA; WNMTATR; - OrthoDB; EOG091G0QVT; - PhylomeDB; Q969F0; - TreeFam; TF338514; - BioCyc; ZFISH:ENSG00000147378-MONOMER; - ChiTaRS; FATE1; human GeneWiki; FATE1; - GenomeRNAi; 89885; - PRO; PR:Q969F0; - Proteomes; UP000005640; Chromosome X Bgee; ENSG00000147378; - CleanEx; HS_FATE1; - ExpressionAtlas; Q969F0; baseline and differential Genevisible; Q969F0; HS GO; GO:0005783; C:endoplasmic reticulum; IDA:LIFEdb GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW InterPro; IPR008518; FATE/Miff/Tango-11 Pfam; PF05644; Miff; 1 1: Evidence at protein level; Complete proteome; Membrane; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix CHAIN 1 183 Fetal and adult testis-expressed transcript protein /FTId=PRO_0000087200 TRANSMEM 163 181 Helical. VARIANT 10 10 A -> V (common polymorphism; 16% of the population; infertile and fertile individuals; dbSNP:rs3810715) /FTId=VAR_016917 VARIANT 34 34 I -> T (in fertile and infertile individuals) /FTId=VAR_016918 VARIANT 125 125 S -> R (in fertile and infertile individuals; dbSNP:rs141497002) /FTId=VAR_016919 SEQUENCE 183 AA; 20712 MW; F3448EDCBCD148CB CRC64; MAGGPPNTKA EMEMSLAEEL NHGRQGENQE HLVIAEMMEL GSRSRGASQK KQKLEQKAAG SASAKRVWNM TATRPKKMGS QLPKPRMLRE SGHGDAHLQE YAGNFQGIRF HYDRNPGTDA VAQTSLEEFN VLEMEVMRRQ LYAVNRRLRA LEEQGATWRH RETLIIAVLV SASIANLWLW MNQ|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Olesen C.,et al.Mol. Cell. Endocrinol. 184:25-32(2001).
Dong X.-Y.,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Olesen C.,et al.Hum. Genet. 113:195-201(2003).
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