|Application ||WB, IHC-P, E|
|Calculated MW||41387 Da|
|Antigen Region||21-52 aa|
|Other Names||Growth/differentiation factor 3, GDF-3, GDF3|
|Target/Specificity||This GDF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-52 amino acids from the N-terminal region of human GDF3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GDF3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
GDF3 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. The function of this protein is unknown, but expression studies suggest it may be involved in regulation of the adult lymphatic and erythroid systems and embryonic development.
Clark, H.F., et al., Genome Res. 13(10):2265-2270 (2003).
Ducy, P., et al., Kidney Int. 57(6):2207-2214 (2000).
Caricasole, A.A., et al., Oncogene 16(1):95-103 (1998).
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