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Myostatin (GDF8) Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Myostatin (GDF8) Antibody (N-term) AP2068a
    Anti-GDF8 Antibody at 1:2000 dilution + mouse liver lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 43 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - Myostatin (GDF8) Antibody (N-term) AP2068a
    Anti-GDF8 Antibody (N24) at 1:2000 dilution + human skeletal muscle lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 43 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • IHC-P - Myostatin (GDF8) Antibody (N-term) AP2068a
    Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with GDF8 antibody (N-term )(Cat.#AP2068a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O14793
Other Accession O18831, Q95J86, O18836, Q9GM97
Reactivity Human, Mouse
Predicted Monkey, Pig, Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 42750 Da
Antigen Region 9-38 aa
Additional Information
Gene ID 2660
Other Names Growth/differentiation factor 8, GDF-8, Myostatin, MSTN, GDF8
Target/Specificity This Myostatin (GDF8) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-38 amino acids from the N-terminal region of human Myostatin (GDF8).
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMyostatin (GDF8) Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms GDF8
Function Acts specifically as a negative regulator of skeletal muscle growth.
Cellular Location Secreted.
Research Areas
Citations (0)

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GDF8 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth.


Hill, J.J., et al., J. Biol. Chem. 277(43):40735-40741 (2002). Hamrick, M.W., et al., Calcif. Tissue Int. 71(1):63-68 (2002). Welle, S., et al., Exp. Gerontol. 37(6):833-839 (2002). Ducy, P., et al., Kidney Int. 57(6):2207-2214 (2000). Ferrell, R.E., et al., Genomics 62(2):203-207 (1999).

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$ 295.00
$ 99.00
Cat# AP2068a
(40 western blots)
Availability: In Stock
Bulk Size
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