|Application ||WB, E|
|Calculated MW||71540 Da|
|Other Names||Platelet glycoprotein Ib alpha chain, GP-Ib alpha, GPIb-alpha, GPIbA, Glycoprotein Ibalpha, Antigen CD42b-alpha, CD42b, Glycocalicin, GP1BA|
|Target/Specificity||This GP1BA(Glycocalicin) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 344-378 amino acids from the Central region of human GP1BA(Glycocalicin).|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GP1BA(Glycocalicin) Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium.
Lopez J.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:5615-5619(1987).
Wenger R.H.,et al.Biochem. Biophys. Res. Commun. 156:389-395(1988).
Matsubara Y.,et al.Thromb. Haemost. 87:867-872(2002).
Matsubara Y.,et al.J. Thromb. Haemost. 1:2198-2205(2003).
Titani K.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:5610-5614(1987).
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