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HUMAN-GAB1(Y259) Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - HUMAN-GAB1(Y259) Antibody AP20723b
    Western blot analysis of lysates from 293, HUVEC, T47D cell line (from left to right), using HUMAN-GAB1(Y259) (Cat. #AP20723b). AP20723b was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q13480
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 76616 Da
Additional Information
Gene ID 2549
Other Names GRB2-associated-binding protein 1, GRB2-associated binder 1, Growth factor receptor bound protein 2-associated protein 1, GAB1
Target/Specificity This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 250-285 amino acids from human.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHUMAN-GAB1(Y259) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GAB1
Function Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR).
Research Areas
Citations (0)

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Background

Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR).

References

Holgado-Madruga M.,et al.Nature 379:560-564(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Brdicka T.,et al.J. Exp. Med. 196:1617-1626(2002).

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$ 295.00
$ 99.00
Cat# AP20723b
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
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Ordering Information

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