|Application ||WB, E|
|Calculated MW||28048 Da|
|Other Names||Sepiapterin reductase, SPR, SPR|
|Target/Specificity||This SPR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 139-170 amino acids from the C-terminal region of human SPR.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SPR Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the final one or two reductions in tetra- hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.|
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Provided below are standard protocols that you may find useful for product applications.
Catalyzes the final one or two reductions in tetra- hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.
Ichinose H.,et al.Biochem. Biophys. Res. Commun. 179:183-189(1991).
Maier J.,et al.Exp. Cell Res. 204:217-222(1993).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).
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