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GLRX5 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - GLRX5 Antibody (Center) AP20754c
    Western blot analysis of lysate from human liver tissue lysate, using GLRX5 Antibody (Center)(Cat. #AP20754c). AP20754c was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q86SX6
Other Accession Q80Y14
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 16628 Da
Additional Information
Gene ID 51218
Other Names Glutaredoxin-related protein 5, mitochondrial, Monothiol glutaredoxin-5, GLRX5, C14orf87
Target/Specificity This GLRX5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 93-127 amino acids from the Central region of human GLRX5.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGLRX5 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GLRX5
Synonyms C14orf87
Function Monothiol glutaredoxin involved in mitochondrial iron-sulfur (Fe/S) cluster transfer (PubMed:20364084, PubMed:23615440). Receives 2Fe/2S clusters from scaffold protein ISCU and mediates their transfer to apoproteins, to the 4Fe/FS cluster biosynthesis machinery, or export from mitochondrion (PubMed:20364084, PubMed:23615440, PubMed:24334290). Required for normal regulation of hemoglobin synthesis by the iron- sulfur protein ACO1 (PubMed:20364084).
Cellular Location Mitochondrion matrix
Research Areas
Citations (0)
citation

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Background

Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters. Required for normal iron homeostasis. Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1.

References

Wingert R.A.,et al.Nature 436:1035-1039(2005).
Wingert R.A.,et al.Nature 437:920-920(2005).
Kurosawa N.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Li W.B.,et al.Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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$ 365.00
$ 140.00
Cat# AP20754c
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