|Application ||WB, E|
|Other Accession||P85970, Q9CVB6, Q3MHR7|
|Predicted||Bovine, Mouse, Rat|
|Calculated MW||34333 Da|
|Other Names||Actin-related protein 2/3 complex subunit 2, Arp2/3 complex 34 kDa subunit, p34-ARC, ARPC2, ARC34|
|Target/Specificity||This ARPC2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 278-311 amino acids from the C-terminal region of human ARPC2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ARPC2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.|
|Cellular Location||Cytoplasm, cytoskeleton. Cell projection. Cell junction, synapse, synaptosome|
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Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
Welch M.D.,et al.J. Cell Biol. 138:375-384(1997).
Couch F.J.,et al.Genomics 36:86-99(1996).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Gevaert K.,et al.Nat. Biotechnol. 21:566-569(2003).
Zhang C.,et al.Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
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