|Application ||WB, E|
|Other Accession||O08589, Q9Z239, Q3SZX0|
|Calculated MW||10441 Da|
|Other Names||Phospholemman, FXYD domain-containing ion transport regulator 1, FXYD1, PLM|
|Target/Specificity||This FXYD1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 69-101amino acids from the C-terminal region of human FXYD1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FXYD1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May have a functional role in muscle contraction. Induces a hyperpolarization-activated chloride current when exogenously expressed.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Highest expression in skeletal muscle and heart. Moderate levels in brain, placenta, lung, liver, pancreas, uterus, bladder, prostate, small intestine and colon with mucosal lining. Very low levels in kidney, colon and small intestine without mucosa, prostate without endothelial lining, spleen, and testis|
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Provided below are standard protocols that you may find useful for product applications.
May have a functional role in muscle contraction. Induces a hyperpolarization-activated chloride current when exogenously expressed.
Chen L.-S.K.,et al.Genomics 41:435-443(1997).
Sweadner K.J.,et al.Genomics 68:41-56(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mounsey J.P.,et al.J. Biol. Chem. 275:23362-23367(2000).
Tulloch L.B.,et al.J. Biol. Chem. 286:36020-36031(2011).
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