|Application ||WB, E|
|Calculated MW||27729 Da|
|Other Names||Synaptonemal complex protein 3, SCP-3, SYCP3, SCP3|
|Target/Specificity||This SYCP3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 13-46amino acids from the N-terminal region of human SYCP3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SYCP3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Has an essential meiotic function in spermatogenesis. May be important for testis development. Required for efficient phosphorylation of HORMAD1 and HORMAD2 (By similarity).|
|Cellular Location||Nucleus. Chromosome. Note=In tripartite segments of synaptonemal complexes, irrespective of whether these are synapsed or unsynapsed.|
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Provided below are standard protocols that you may find useful for product applications.
Component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Has an essential meiotic function in spermatogenesis. May be important for testis development. Required for efficient phosphorylation of HORMAD1 and HORMAD2 (By similarity).
Martinez-Garay I.,et al.Genomics 80:259-267(2002).
Adamah D.J.B.,et al.Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases.
Miyamoto T.,et al.Lancet 362:1714-1719(2003).
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