|Application ||WB, E|
|Other Accession||P19357, P14142|
|Calculated MW||54787 Da|
|Other Names||Solute carrier family 2, facilitated glucose transporter member 4, Glucose transporter type 4, insulin-responsive, GLUT-4, SLC2A4, GLUT4|
|Target/Specificity||This SLC2A4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 495-529 amino acids from the C-terminal region of human SLC2A4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SLC2A4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Insulin-regulated facilitative glucose transporter.|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein. Cytoplasm, perinuclear region. Note=Localizes primarily to the perinuclear region, undergoing continued recycling to the plasma membrane where it is rapidly reinternalized. The dileucine internalization motif is critical for intracellular sequestration|
|Tissue Location||Skeletal and cardiac muscles; brown and white fat|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Insulin-regulated facilitative glucose transporter.
Fukumoto H.,et al.J. Biol. Chem. 264:7776-7779(1989).
Buse J.B.,et al.Diabetes 41:1436-1445(1992).
Chiaramonte R.,et al.Gene 130:307-308(1993).
Verhey K.J.,et al.J. Biol. Chem. 269:2353-2356(1994).
Lalioti V.S.,et al.J. Biol. Chem. 277:19783-19791(2002).
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