|Application ||WB, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||44965 Da|
|Other Names||Plasminogen activator inhibitor 1 RNA-binding protein, PAI1 RNA-binding protein 1, PAI-RBP1, SERPINE1 mRNA-binding protein 1, SERBP1, PAIRBP1|
|Target/Specificity||This SERBP1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 149-183 amino acids from the Central region of human SERBP1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SERBP1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay.|
|Cellular Location||Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Note=Also found in perinuclear regions|
|Tissue Location||Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay.
Lai C.-H.,et al.Genome Res. 10:703-713(2000).
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.
1 2 3 4 5
1. Block with 3% skim milk for 1 hour at room temperature. 2. Incubate overnight with Abgent primary antibody 1:1000 in 3% skim milk at 4℃ 3. Wash 5*5 min with TBST. 4. Incubate with HRP-conjugated secondary antibody 1:5000 in 3% skim milk for 1 hour at room temperature. 5. Wash 5*5 min with TBST. 6. Incubate with ECL substrates and expose